Wayne & Mary's Nutrition Center
1518 South Sycamore Ave
Sioux Falls, SD 57110 Map
Phone: (605) 332-5985

Wayne & Mary's Nutrition Center
3700 S Kiwanis Ave Ste 1
Sioux Falls, SD 57105 Map
Phone: (605) 332-1717


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Get The Information & Products You Need For A Healthy Lifestyle!

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Since 1970, Wayne and Mary's has been the region’s trusted source for natural health solutions. Why? 

  • We guarantee our products! We carry the most effective, tested products on the market. Nutrition can take some trial and error, so if a product doesn’t work for you, we’ll help you find a better fit!

  • Our team of nutrition experts can answer your questions and guide you to the right nutrients for your situation. Your results are our #1 priority! 

  • Our education is top notch–our team is committed to in-person seminars and monthly education from national experts! 

  • We offer special orders so you can get exactly what you need! 

  • We ship products directly to you! 

  • We’ve earned the trust of a variety of partners in health in the region–doctors, nurses, nurse practitioners, pharmacists, herbalists, and other practitioners who refer clients to us regularly for the highest-quality products.


"People that work there are knowledgeable friendly and willing to assist you in your needs I love to shop there"- Lisa D.

"We just stumbled upon this store driving through. What a gem! So many good finds."- Krista D.

"Had a great experience ordering over the phone today. Very knowledgeable caring staff!"- Megan A.

"Always so friendly, knowledgeable and its such a calming place to shop at. Love all the great choices in products."- Angelique V.